Volume 18, Issue 1, Winter 2007, Page 1-90
Effects of Acetylsalicylic Acid on Ethanol – Induced Intrauterine Fetal Growth Restriction in Rats
Rafidain Journal of Science,
2007, Volume 18, Issue 1, Pages 1-7
DOI:
10.33899/rjs.2007.42615
The effects of acetylsalicylic acid (ASA) on intrauterine growth restriction induced by maternal ethanol consumption were studied. A single intraperitoneal dose of ethanol (2.96 g/kg body weight) injected in the 10th day of pregnancy (PD10), significantly reduced maternal weight gain, fetal weight, amniotic fluid volume and umbilical cord length. Meanwhile, ethanol did not affect placental weight or litter size. A single intraperioneal dose of ASA (200 mg/g body weight). Injected on the PD10, did not modify maternal body weight gain, litter size, fetal and placental weight and amniotic fluid volume, but significantly diminished umbilical cord length. Intraperitoneal injections of ASA (200 mg/g body weight) and ethanol (2.96 g/kg length weight) on PD10. demonstrated that ASA antagonized in part at least, the effects of ethanol on maternal weight gain, fetal weight and amniotic fluid volume. Contrarily, ASA potentiated the effect of ethanol on umbilical cord length.
Antimutagenicity of Extracts of Three Edible Plants from Mosul City (Iraq) in Conidia of Aspergillus amstelodami
Rafidain Journal of Science,
2007, Volume 18, Issue 1, Pages 8-19
DOI:
10.33899/rjs.2007.42636
The potential antimutagenic action of extracts of three common edible plants in Mosul was tested in conidia of the ascomycetous fungus Aspergillus amstelodami. Extracts of leaves of celery(Apium graveolens Linn) and parsley (Petroselinum sativum Hoffn.) and the round roots of radish (Raphanus sativus Linn.) were made in water, methanol, ethylacetate or petroleum ether. The antimutagenic action was sought in the reduction of frequency of spontaneous and induced (by 8-Methoxypsoralen + Near UV, 8-MOP + NUV) mutants resistant to 8-azaguanine. Three final concentrations in the growth medium of each extract were tested. These were (μg/ml) 800, 1600 and 3200 for celery and parsley and 600, 800 and 1200 for radish. The water extract of celery was ineffective while its concentration 3200 in methanol in ethylacetate and all three concentrations in the petroleum ether were effective in reducing the frequency of induced resistant mutants. Extracts of parsley behaved similarly. Extracts of the radish roots were all ineffective at all concentrations tested except the concentration 1200 of the water extract. The effect of the radish water is attributed to peroxidases and oxidases while those of celery and parsley to some lipid-soluble components which were sequentially concentrated in the petroleum ether according to the extraction protocol used.
Furthermore, none of the extracts by itself or in combinations with 8-MOP alone or NUV alone was found effective in significantly altering the frequency of the spontaneous mutants. This was taken to indicate that the extracts by themselves did not act as mutagenis or synergistic mutagens or photosensitizers to NUV. Moreover, their action on the positive mutagen (8-MOP + NUV) and not on the spontaneous frequencies suggests that these extracts behaved as desmutagens acting on the mutagen rather than as bioantimutagens acting directly on DNA.
Effect of Polymeric Chain Flexibility on Electrical Conductivity of Aromatic Polyesters
Rafidain Journal of Science,
2007, Volume 18, Issue 1, Pages 20-27
DOI:
10.33899/rjs.2007.42638
Two types of aromatic polyesters were prepared by polycondensation of terephthaloyl dichloride with 2,7-dihydroxy naphthalene (polymer 1) and bis(4,4′-di-α-naphthoyl) methane (polymer 2). The electrical conductivity of polymer 2 is larger than that of polymer 1. The reason is the polymers chain mobility. The effect of doping by ferric chloride and temperature on electrical conductivity was studied. It was noticed that the doping process increased the conductivity of polymer 1 more than polymer 2. The temperature well increase the electrical conductivity of purred polymer in a manner that the activation energy of polymer 2 is larger than that of polymer 1.
Spectrophotometric Assay of Thymol in Various Samples by Coupling with Diazotized p-Nitroaniline
Rafidain Journal of Science,
2007, Volume 18, Issue 1, Pages 28-37
DOI:
10.33899/rjs.2007.42640
A simple and rapid spectrophotometric method for the trace determination of trace amount of thymol in various samples has been established. The method is based on the coupling reaction of thymol with diazotized p-nitroaniline in basic medium to form an intense pinkish-red, water-soluble and stable mono azo dye which shows maximum absorption at 513nm. A plot of absorbance with thymol concentration gives a straight line indicating that Beer’s law has been obeyed over the range 1-300 g/25ml, i.e., 0.04-12 ppm with a molar absorptivity of 2.48104 l mol-1 cm-1, and Sandell sensitivity index of 0.006 g/cm2. The method does not resort to neither temperature control nor to solvent extraction. The effect of organic solvents on the spectrophotometric properties of the azo dye, the composition and stability constant and interference due to foreign compounds have been worked out. The method has been applied to the determination of thymol in pharmaceutical, oil and waters.
Synthesis, Characterization and Biological Studies of Selenium Dithiocarbamates and their Ni+2 and Cu+2 Complexes
Rafidain Journal of Science,
2007, Volume 18, Issue 1, Pages 38-47
DOI:
10.33899/rjs.2007.42642
Selenium metal react with (RNHC(S)S)2 where R= (Ph or o-tolyl) in refluxing toluene to give the compounds Se{RNHC(S)S}4. New complexes of the type [M2Se{RNHC(S)S}4Cl4], where M=Ni+2 or Cu+2, were prepared by reaction of Se{RNHC(S)S}4 with the metal chloride salts in 1:2 molar ratio.The compounds and complexes were characterized by atomic absorption, Infrared, U.V-Visible spectra, conductivity and magnetic measurements.Biological activity studies of the compounds and complexes as antimicrobial agents and the comparison of their activities with well known antibiotic (Ampicillinc, Gentamycine and Nystatine) using different straine of bacteria gram (+ve) and gram (-ve) in addition to fungi strain candida albicans.
The results indicated that complexes of the type [M2Se{S2CNHPh}4Cl4] are more active than [M2Se{S2CNHPhCH3-o}4 Cl4] while the selenium compounds Se(S2CNHPh)4 and Se(S2CNHPhC2H5)4 have moderate antimicrobial activity.
Antioxidants and Some Biochemical Parameters in Alcoholism in Mosul City
Rafidain Journal of Science,
2007, Volume 18, Issue 1, Pages 48-58
DOI:
10.33899/rjs.2007.42645
The study was conducted in Mosul city to show the effects of alcoholism on antioxidants and some biochemical parameters which include: Vitamin E, Vitamin A, β-carotene, Vitamin C, Folic acid, Ceruloplasmin (Cp), Total protein, Albumin, Calcium, Total bilirubin, Direct bilirubin, Uric acid, Creatinine, Total iron binding capacity (TIBC), Iron, Glutathione(GSH), Malondialdehyde (MDA), Cholesterol, Glucose, Selenium and Transferrin saturation (%). The study included (103) persons represented in two groups, the first group as a control included outside city center living, the second group represented for alcoholism was divided into two sub groups, smokers and non smokers.
The results showed a significant decreased in: calcium, transferrin saturation (%), but non decreased significant in: vitamin A, total bilirubin, direct bilirubin, creatinine, iron, MDA and glucose. While a significant increased in TIBC and selenium, but non significant increased in: vitamin E, β-carotene, vitamin C, folic acid, Cp., total protein, albumin, uric acid, GSH and cholesterol.
The results also showed a significant decrease of alcoholism smokers in: vitamin A (P=0.004), vitamin C, transferrin saturation (%) and folic acid, and non significant in: total iron binding capacity, iron, vitamin E, β-carotene, total protein, albumin and creatinine. While non significant increase in: Cp., calcium, total bilirubin, direct bilirubin, uric acid, malondialdehyde, glutathion, cholesterol, glucose and selenium was detected.
Design Enhancement of the 460 GHz, Second Harmonic Gyrotron Oscillator Through Its Dispersion Diagram
Rafidain Journal of Science,
2007, Volume 18, Issue 1, Pages 59-67
DOI:
10.33899/rjs.2007.42691
All high power radio frequency (RF) sources have their own dispersion diagram, giving the relation between the output frequency of the device and the axial wave number component of the operating waveguide wave mode. This diagram gives the most important characteristics about the source and in this work it was used as a tool for the device design enhancement. From this diagram one can change the input design parameters in order to get the best dispersion diagram fitting with standard one. In this work, the dispersion diagram for the 460 GHz second harmonic gyrotron oscillator studied previously by Hornstein (2001) was plotted and the main characteristics of these kinds of gyrotrons were observed from the diagram which replies the precision of the design.
Origin of Ga’ara and Hussainiyat Clays, Iraqi Western Desert
Rafidain Journal of Science,
2007, Volume 18, Issue 1, Pages 68-80
DOI:
10.33899/rjs.2007.42693
The two Formations Ga’ara and the lower clastic unit of Hussainiyat were deposited in fluvial system of deposition with slight different behaviors like the thickness of fining upward cycles in different times, in addition to, some stratigraphic, structural, paleogeographic and geochemical evidences.
The present work aimed to compare between these formations from sedimentological and geochemical points of view. It has been found that both formations were derived from the same source of the western and southwestern Arabian shield.
Geomorphologic Map of Nineveh Governorate, Northwestern Iraq Using Visual Image Interpretation
Rafidain Journal of Science,
2007, Volume 18, Issue 1, Pages 81-90
DOI:
10.33899/rjs.2007.42694
For academic and practical purposes, this map project had the following components:
1-Compiling a geomorphic map as the basis for establishing a database and publishing a full-view map at a scale of 1: 250,000 using visual image interpretation
2-Classification and mapping of basic landform units, landform types that are relatively uniform in genesis and relief forms.
The study area consists of three main genetic groups of landforms based on units of tectonic, fluvial and denudation landform types, subdivided into 14 subunits. Each landform assemblage reflects a different balance between the various endogenic and exogenic processes of landscape evolutions in northern Iraq since late Miocene.
These data were utilized to draw a regional geomorphologic map for the Nineveh Governorate, showing the relationship between landform units and various geomorphic processes. The contents of this map were produced following the scheme devised by the ITC textbook. This map was finalized in 2006 at the Remote Sensing Center, in Mosul University.