Histopathological Examination of Uterine Tumors and Endometrial Hyperplasias Colonized by Streptococcus agalactiae and Antibiotic Susceptibility of the Isolated Streptococcus agalactiae
Rafidain Journal of Science,
2012, Volume 23, Issue 1, Pages 34-43
AbstractStreptococcus agalactiae was isolated from six leiomyomas of the uterus and two endometrial hyperplasia cases collected from women aged 35 to 80 years, underwent Total Abdominal Hysterectomy (TAH) in Basrah Maternity and Child Hospital due to continuous vaginal bleeding not responding to medical treatment. Sections of leiomyomas stained with haematoxylin and eosin illustrate proliferating smooth muscles fibers with intervening fibrous tissue. Sections from endometrial hyperplasia stained with modified Gram stain demonstrated S. agalactiae as diplococci or as aggregates.
Resistance of S. agalactiae isolated from the above eight cases, against 14 antibiotics was determined. Results clarified that all isolates (100%) are resistant to 10 antibiotics: tetracyclin, erythromycin, cefotaxine, ampicillin, chloramphenicol, penicillin, cloxacillin, cephalothin, gentamycin and tobramycin. Most isolates demonstrated susceptibility to amoxicillin (62.5 %) which makes it the drug of choice against S. agalactiae. Four isolates of S. agalactiae (50%) were resistant to vancomycin, which raises a threat of vancomycin resistance genes being transferred to other gram-positive species found in the vaginal and rectal sites.
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