The COVID-19 pandemic, precipitated by SARS-CoV-2, has become a defining global health crisis of the 21st century, demonstrating the capacity of infectious diseases to cause widespread morbidity, mortality, and societal upheaval. This investigation seeks to dissect and contrast the symptomatic expression of acute and post-acute COVID-19 phases and explore traditional medicine's impact on disease progression and the emergence of complications. A quantitative cross-sectional approach involving 450 adult participants with laboratory-confirmed COVID-19 was employed. Selection adhered to specified inclusion criteria with data from internet-based questionnaires between July 5 and August 7, 2021. The study rigorously scrutinized clinical symptoms during the infection and recovery phases and assessed the contribution of traditional medicinal practices to complication management. The research design, population, data collection methods, analysis, and ethical compliance are meticulously outlined to elucidate the research process. Traditional medicinal remedies were notably prevalent among participants, with a marked utilization reported during the infection phase. The analysis indicated that those engaging in traditional medicine experienced milder symptoms acutely and a decreased frequency of persistent post-COVID-19 symptoms, suggesting a beneficial modulation of immune function.