A Brief Review of Novel Coronavirus
AbstractSince December 2019, the novel Coronavirus (SARS-CoV-2), which has emerged in China, has drawn global interest due to its quick spread, which affects more than 221 countries and territories worldwide and many of external transportations. Covid-2019 is a severe acute respiratory syndrome of viral pneumonia. After the (SARS CoV-1) of the 21st Century and the Coronavirus Respiratory Syndrome of Middle East, the emergence of Covid-19 has been established as the third entrance of a potential pathogen Coronavirus. Due to a lack of proofreading activity for viral RNA polymers, single-stranded RNA viruses show a higher biological mutation rate; however, CoV has minimal proofreading abilities, as the nsp14 protein allows members of the CoV family to increase the size of the genome, unlike the other RNA viruses that are susceptible to mutations, with the exception of the Arenaviridae family.
The wide range of new discoveries has brought importance to coronavirus researches and strategic expansion is important to accept the newest innovations and advances. This review extensively summarizes the genetic structure, cause of COVID-19 infection and detection to assist with follow-up research, prevention and to provide the current information to the readers.
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