The research included a biochemical study of patients with duodenal ulcer (DU). Histological biopsies were taken for the pathological and bacteriological tests, investigating H pylori infection. Blood (76 samples) and gastric juice (61 samples) were taken from patients with DU. The measured parameters in sera included :Vitamin C, Vitamin E, Vitamin A, Pepsinogen, total protein, albumin, chloride, iron, hemoglobin and blood groups, whereas in gastric juice included: vitamin C, Pepsinogen, chloride, total protein and urea.
The results showed a significant decrease in vitamin C, vitamin E, vitamin A, iron and hemoglobin concentration in the serum of patients with DU, in comparison with control group, for both sexes. Pepsinogen was also found to be increased significantly in both blood and gastric juice of patients with DU, for both sexes. A significant increase in blood and gastric juice chloride concentration was found for patients with DU for both sexes. The results had also shown no significant difference in blood total protein concentration for patients with DU whereas a significant decrease in gastric juice protein concentration was noticed for patients with DU for both sexes. It had pointed that serum albumin concentration was within the normal range for patients with DU for both sexes. Finally the results had demonstrated a significant decrease in gastric juice urea and vitamin C concentration for patients with DU in comparison with control group for both sexes. However, the results had also confirmed that persons with blood group O+ are more liable to have duodenal ulcer .